Hormonal Issues & Considerations for Fat Burning & Weight Control

In this post, I introduce key hormones that directly or indirectly affect fat burning. This article is not about weight loss, but it is about fat loss. The difference is people may lose weight by losing fluid, glycogen, muscle, and even bone density. However, of course, no one wants to lose valuable muscle and critical bone density for the sake of losing weight. Thus, my focus is losing fat, more precisely, using fat as energy for sustainable vitality, fitness, and health.

From my experience and research, the most impactful hormone on fat loss is insulin. Let me explain what insulin and particularly insulin resistance means for fat loss or fat gain. While insulin has multiple roles in our metabolic health, one of the critical roles of insulin is to manage glucose in our bloodstream. Our bodies cannot handle excessive sugar and regard it as toxic. We can measure and monitor blood glucose.

In fact, in simple terms, the acceptable sugar level in the bloodstream is believed to be equivalent to a teaspoon at a given time. This gives a guide for consuming carbohydrates, especially the refined ones.

Elevated blood glucose is known as a health condition called hyperglycemia. This condition is a kind of glucose toxicity causing nephropathy, neuropathy, reactive oxygen species.

When our bloodstream experiences hyperglycaemia, the insulin hormone can spike. The purpose of this metabolic reaction is to prevent blood from glucose toxicity. At first attempt, insulin sends signals to cells in various organs to use the glucose. However, if cells of those organs, such as muscles, cannot use the offered glucose, our body has a mechanism to turn the glucose into fat.

So in simple terms, the eye-opening scientific finding is that sugar can turn into fat. Many medical textbooks and scientific papers documented this fact. For details, you can check this paper titled “From Sugar to Fat” explaining lipogenesis occurring in the liver, where dietary carbohydrates control the expression of key enzymes in glycolytic and lipogenic pathways.

One key piece of information is that after excessive use of insulin, we experience a phenomenon called “insulin resistance”. It means that our cells cannot get the required signals from insulin. They stop responding to signals. The bloodstream may need more insulin to function. Insulin resistance is a common condition and one of the root causes of Type 2 diabetes .

Fat utilization is associated with hunger. Hormones also control our hunger and satiety feelings. Thus, the second critical hormone associated with fat loss is leptin. To understand the role of leptin, we also need to know its antagonist hormone, ghrelin. These two hormones are chemical messengers running the metabolic show in our body. These hormones are like “yin-yang”. They work together. It means that while ghrelin increases hunger, leptin lowers it. So, when one hormone is active the other one gets passive.

Ghrelin hormone makes us hungry. The goal is to feed our bodies and obtain vital energy from food. For example, we need protein, dietary fat, minerals, and vitamins to nurture our cells. Without ghrelin, our body will not know when we need nutritional support.

However, our body has a specific capacity for food. It is unique for each person. So after a while, we need to stop eating. This mechanism is realized by leptin which makes us feel satisfied and prevents us from overeating. So leptin is a satiety hormone. Ideally, these hormones work well until a tricky situation happens.

The trick is caused by leptin. Similar to insulin, there is also a phenomenon called “leptin resistance”. The tricky bit with leptin is a condition known as “leptin resistance”. This condition causes excessive and unnecessary hunger. As mentioned before, leptin instructs the brain to stop eating. If we have “leptin resistance”, our brain does not get the signal from the leptin hormone. Thus, we feel hungry even if we eat more than what we need.

Further Reading

We are all unique and experience various situations and solve our problems using different methods.

However, learning from the body of knowledge and experiences of other people can give us valuable perspectives to customize our solutions.

I posted several articles about my health and fitness journey. I hope some of these stories can give you useful perspectives.

Fix Metabolic Syndrome, Live a Longer and Healthier Life: Metabolic inflexibility underlies major health issues.

Major Causes of Non-Alcoholic Fatty Liver Disease: It looks like too much food, particularly sugar can fatten the liver. Here is what science says.

Fat loss had nothing to do with calories.

Why Fat Loss Has Nothing to Do With Calories.

Why I Don’t Snack Anymore: Snacks never worked for me. I found the reasons later, after suffering a lot.

Eliza Shed 30 Pounds In Six Months With Two Tips: And Never Gained Them Again.

Why & How Eliza Lost 30 Pounds of Fat in Six Months?

How I Naturally & Easily Fixed My Leaky Gut: After severely suffering from digestive discomfort, allergies, inflammation, and autoimmune disorders over a decade.

Why Is Activated Charcoal in My Emergency Bag? Is It Hype or Hope?

How I Defeated Arthritis: My journey to overcoming inflammation and freeing from pain.

Fixing Allergies And Autoimmune Conditions With Elimination Diet: My personal experience on eliminating offensive food from my diet.

Powerful Life-Changing Hacks That Truly Transformed My Life: Smart Sleep Habits.

Dealing With Anxiety in Difficult Times: How to understand anxiety symptoms, root causes, distinguish anxiety from fear, take practical & effective measures to cope.

Healing Mild Depression By Scheduling And Prioritizing Fun: We need to trick the mind by planning pleasure.

Loneliness Is In The Mind: I Used To Feel Lonely; It Was Unbearable.

Tricking Brain To Stop Smoking: My personal story on how I quitted smoking 40 years ago and never smoked again.

Emotional Stress As Larger Part Of The Iceberg In Energy Deficiency: Emotional stress and drained energy can prevent us from living a satisfying life.

I Fixed My Brain Fog With 7 Simple Hacks: After a decade of trial and error, I found some practical ways to overcome brain fog and prevent it from happening again.

Preventing Gum Disease With A Simple Hack: No more debris, plaque, and bacterial colonization in my mouth.

My Unusual Diet Revealed: How a carnivore lifestyle transformed my health and fitness.

Fixing Allergies And Autoimmune Conditions With Elimination Diet: My personal experience on eliminating offensive food from my diet.

Why Is It So Hard to Get Rid of Loose Skin?: And how can we speed up the elimination process.

How To Get Six-Pack Abs Without Destroying Our Health: The desire for six-pack abs may create trauma. What if I tell you there are easier, more effective ways to get it?

A Holistic View of Biohacking from Multiple Perspectives.

About the Author

I am a technologist, postdoctoral researcher, published author, editor, and digital marketing strategist with four decades of industry experience.

I write articles for Medium, News Break, and Vocal Media. On Medium, I established ILLUMINATION, ILLUMINATION-Curated, ILLUMINATION’ S MIRROR, ILLUMINATION Book Chapter, Technology Hits, and SYNERGY publications supporting 11,000+ writers on Medium.

You may join my publications requesting access here.

Heath, Fitness, & Lifestyle Topics Collected on Transhumanism Leadership: Eclectic articles addressing interesting and important life matters for individuals and society

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